The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties

Targeted disruption of both alleles of mouse sos1, which encodes a Ras-specific exchange factor, conferred mid-gestational embryonic lethality that was secondary to impaired placental development and was associated with very low placental ERK activity. The trophoblastic layers of sos1(–/–) embryos w...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Qian, Xiaolan, Esteban, Luis, Vass, William C., Upadhyaya, Cheerag, Papageorge, Alex G., Yienger, Kate, Ward, Jerrold M., Lowy, Douglas R., Santos, Eugenio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
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Articles
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305602/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10675333/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.4.642
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