The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties
Targeted disruption of both alleles of mouse sos1, which encodes a Ras-specific exchange factor, conferred mid-gestational embryonic lethality that was secondary to impaired placental development and was associated with very low placental ERK activity. The trophoblastic layers of sos1(–/–) embryos w...
Guardat en:
| Publicat a: | EMBO J |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305602/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10675333/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.4.642 |
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