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Gene-Trap Mutagenesis Identifies Mammalian Genes Contributing to Intoxication by Clostridium perfringens ε-Toxin

The Clostridium perfringens ε-toxin is an extremely potent toxin associated with lethal toxemias in domesticated ruminants and may be toxic to humans. Intoxication results in fluid accumulation in various tissues, most notably in the brain and kidneys. Previous studies suggest that the toxin is a po...

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Detalhes bibliográficos
Main Authors: Ivie, Susan E., Fennessey, Christine M., Sheng, Jinsong, Rubin, Donald H., McClain, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055893/
https://ncbi.nlm.nih.gov/pubmed/21412435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017787
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