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The Myelin and Lymphocyte Protein MAL Is Required for Binding and Activity of Clostridium perfringens ε-Toxin

Clostridium perfringens ε-toxin (ETX) is a potent pore-forming toxin responsible for a central nervous system (CNS) disease in ruminant animals with characteristics of blood-brain barrier (BBB) dysfunction and white matter injury. ETX has been proposed as a potential causative agent for Multiple Scl...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: Rumah, Kareem Rashid, Ma, Yinghua, Linden, Jennifer R., Oo, Myat Lin, Anrather, Josef, Schaeren-Wiemers, Nicole, Alonso, Miguel A., Fischetti, Vincent A., McClain, Mark S., Vartanian, Timothy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439126/
https://ncbi.nlm.nih.gov/pubmed/25993478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004896
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