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Dominant-negative Inhibitors of the Clostridium perfringens ϵ-Toxin
The Clostridium perfringens ϵ-toxin is responsible for a severe, often lethal intoxication. In this study, we characterized dominant-negative inhibitors of the ϵ-toxin. Site-specific mutations were introduced into the gene encoding ϵ-toxin, and recombinant proteins were expressed in Escherichia coli...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785577/ https://ncbi.nlm.nih.gov/pubmed/19720828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.021782 |
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