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Identification of Small Molecule Inhibitors of Clostridium perfringens ε-Toxin Cytotoxicity Using a Cell-Based High-Throughput Screen

The Clostridium perfringens epsilon toxin, a select agent, is responsible for a severe, often fatal enterotoxemia characterized by edema in the heart, lungs, kidney, and brain. The toxin is believed to be an oligomeric pore-forming toxin. Currently, there is no effective therapy for countering the c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lewis, Michelle, Weaver, Charles David, McClain, Mark S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922765/
https://ncbi.nlm.nih.gov/pubmed/20721308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins2071825
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