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Identification of amino acids important for binding of Clostridium perfringens epsilon toxin to host cells and to HAVCR1

Clostridium perfringens epsilon toxin belongs to the aerolysin-like family of pore-forming toxins and is one of the most potent bacterial toxins known. The epsilon toxin causes fatal enterotoxemia in sheep, goats, and possibly humans. Evidence indicates that the toxin binds to protein receptors incl...

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Bibliographic Details
Main Authors: Ivie, Susan E., McClain, Mark S.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534817/
https://ncbi.nlm.nih.gov/pubmed/22938730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300690a
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