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Impaired germinal center reaction in mice with short telomeres
Reduction of germinal center reactivity is a landmark of immunosenescence and contributes to immunological dysfunction in the elderly. Germinal centers (GC) are characterized by extensive clonal expansion and selection of B lymphocytes to generate the pool of memory B cells. Telomere maintenance by...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305584/ https://ncbi.nlm.nih.gov/pubmed/10654945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.3.472 |
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