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Irregular telomeres impair meiotic synapsis and recombination in mice
Telomere shortening can lead to chromosome instability, replicative senescence, and apoptosis in both somatic and male germ cells. To study roles for mammalian telomeres in homologous pairing and recombination, we characterized effects of telomere shortening on spermatogenesis and oogenesis in late-...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC404073/ https://ncbi.nlm.nih.gov/pubmed/15084742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400755101 |
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