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Irregular telomeres impair meiotic synapsis and recombination in mice

Telomere shortening can lead to chromosome instability, replicative senescence, and apoptosis in both somatic and male germ cells. To study roles for mammalian telomeres in homologous pairing and recombination, we characterized effects of telomere shortening on spermatogenesis and oogenesis in late-...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Lin, Franco, Sonia, Spyropoulos, Barbara, Moens, Peter B., Blasco, Maria A., Keefe, David L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC404073/
https://ncbi.nlm.nih.gov/pubmed/15084742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400755101
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