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Irregular telomeres impair meiotic synapsis and recombination in mice

Telomere shortening can lead to chromosome instability, replicative senescence, and apoptosis in both somatic and male germ cells. To study roles for mammalian telomeres in homologous pairing and recombination, we characterized effects of telomere shortening on spermatogenesis and oogenesis in late-...

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Bibliografski detalji
Glavni autori: Liu, Lin, Franco, Sonia, Spyropoulos, Barbara, Moens, Peter B., Blasco, Maria A., Keefe, David L.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC404073/
https://ncbi.nlm.nih.gov/pubmed/15084742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400755101
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