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Telomerase gene therapy ameliorates the effects of neurodegeneration associated to short telomeres in mice

Neurodegenerative diseases associated with old age such as Alzheimer’s disease present major problems for society, and they currently have no cure. The telomere protective caps at the ends of chromosomes shorten with age, and when they become critically short, they can induce a persistent DNA damage...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Whittemore, Kurt, Derevyanko, Aksinya, Martinez, Paula, Serrano, Rosa, Pumarola, Martí, Bosch, Fàtima, Blasco, Maria A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555470/
https://ncbi.nlm.nih.gov/pubmed/31140977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101982
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