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Structural basis of high fidelity DNA synthesis by yeast DNA polymerase delta
DNA polymerase δ (Polδ) is a high fidelity polymerase that plays a central role in replication from yeast to humans. We present here the crystal structure of the catalytic subunit of yeast Polδ in ternary complex with a template-primer and an incoming nucleotide. The structure, determined at 2.0Å re...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3055789/ https://ncbi.nlm.nih.gov/pubmed/19718023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1663 |
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