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The Presynaptic Component of the Serotonergic System is Required for Clozapine's Efficacy
Clozapine, by virtue of its absence of extrapyramidal side effects and greater efficacy, revolutionized the treatment of schizophrenia, although the mechanisms underlying this exceptional activity remain controversial. Combining an unbiased cheminformatics and physical screening approach, we evaluat...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Nature Publishing Group
2011
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3055689/ https://ncbi.nlm.nih.gov/pubmed/21048700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.195 |
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