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Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

Alzheimer's disease (AD) is a neurodegenerative disorder characterized clinically by cognitive impairments that progress to dementia and death. The earliest symptoms of AD present as a relatively pure deficit in memory retrieval. Therefore, drug treatments that intervene in the early stages of...

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Bibliografische gegevens
Hoofdauteurs: Kilgore, Mark, Miller, Courtney A, Fass, Daniel M, Hennig, Krista M, Haggarty, Stephen J, Sweatt, J David, Rumbaugh, Gavin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055373/
https://ncbi.nlm.nih.gov/pubmed/20010553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2009.197
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