Pharmacological Selectivity Within Class I Histone Deacetylases Predicts Effects on Synaptic Function and Memory Rescue

Histone deacetylases (HDACs) are promising therapeutic targets for neurological and psychiatric disorders that impact cognitive ability, but the relationship between various HDAC isoforms and cognitive improvement is poorly understood, particularly in mouse models of memory impairment. A goal shared...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Rumbaugh, Gavin, Sillivan, Stephanie E, Ozkan, Emin D, Rojas, Camilo S, Hubbs, Christopher R, Aceti, Massimiliano, Kilgore, Mark, Kudugunti, Shashi, Puthanveettil, Sathyanarayanan V, Sweatt, J David, Rusche, James, Miller, Courtney A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538358/
https://ncbi.nlm.nih.gov/pubmed/25837283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.93
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