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Histone Deacetylase Inhibition via RGFP966 Releases the Brakes on Sensory Cortical Plasticity and the Specificity of Memory Formation

Research over the past decade indicates a novel role for epigenetic mechanisms in memory formation. Of particular interest is chromatin modification by histone deacetylases (HDACs), which, in general, negatively regulate transcription. HDAC deletion or inhibition facilitates transcription during mem...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Bieszczad, Kasia M., Bechay, Kiro, Rusche, James R., Jacques, Vincent, Kudugunti, Shashi, Miao, Wenyan, Weinberger, Norman M., McGaugh, James L., Wood, Marcelo A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579377/
https://ncbi.nlm.nih.gov/pubmed/26400942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0914-15.2015
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