Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation

Macrophages, a key cellular component of inflammation, become functionally polarized in a signal- and context-specific manner. Th2 cytokines such as interleukin 4 (IL-4) polarize macrophages to a state of alternative activation that limits inflammation and promotes wound healing. Alternative activat...

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Main Authors: Mullican, Shannon E., Gaddis, Christine A., Alenghat, Theresa, Nair, Meera G., Giacomin, Paul R., Everett, Logan J., Feng, Dan, Steger, David J., Schug, Jonathan, Artis, David, Lazar, Mitchell A.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2011
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243058/
https://ncbi.nlm.nih.gov/pubmed/22156208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.175950.111
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