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The Role of Histone Deacetylase 6 in Synaptic Plasticity and Memory
Histone deacetylases (HDACs) have been extensively studied as drug targets in neurodegenerative diseases but less is known about their role in healthy neurons. We tested zinc-dependent HDACs using RNAi in Drosophila melanogaster and found memory deficits with RPD3 and HDAC6. We demonstrate that HDAC...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5387061/ https://ncbi.nlm.nih.gov/pubmed/28178513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.01.028 |
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