Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway

PURPOSE: Deoxycytidine kinase (dCK) is a rate-limiting enzyme in deoxyribonucleoside salvage, a metabolic pathway involved in the production and maintenance of a balanced pool of deoxyribonucleoside triphosphates (dNTPs) for DNA synthesis. dCK phosphorylates and therefore activates nucleoside analog...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Schwarzenberg, Johannes, Radu, Caius G., Benz, Matthias, Fueger, Barbara, Tran, Andrew Q., Phelps, Michael E., Witte, Owen N., Satyamurthy, Nagichettiar, Czernin, Johannes, Schiepers, Christiaan
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2010
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053458/
https://ncbi.nlm.nih.gov/pubmed/21127859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-010-1666-z
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky