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Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway
PURPOSE: Deoxycytidine kinase (dCK) is a rate-limiting enzyme in deoxyribonucleoside salvage, a metabolic pathway involved in the production and maintenance of a balanced pool of deoxyribonucleoside triphosphates (dNTPs) for DNA synthesis. dCK phosphorylates and therefore activates nucleoside analog...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3053458/ https://ncbi.nlm.nih.gov/pubmed/21127859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-010-1666-z |
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