Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway

PURPOSE: Deoxycytidine kinase (dCK) is a rate-limiting enzyme in deoxyribonucleoside salvage, a metabolic pathway involved in the production and maintenance of a balanced pool of deoxyribonucleoside triphosphates (dNTPs) for DNA synthesis. dCK phosphorylates and therefore activates nucleoside analog...

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Detalhes bibliográficos
Principais autores: Schwarzenberg, Johannes, Radu, Caius G., Benz, Matthias, Fueger, Barbara, Tran, Andrew Q., Phelps, Michael E., Witte, Owen N., Satyamurthy, Nagichettiar, Czernin, Johannes, Schiepers, Christiaan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053458/
https://ncbi.nlm.nih.gov/pubmed/21127859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-010-1666-z
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