Novel Positron Emission Tomography Probes Specific for Deoxycytidine Kinase

Deoxycytidine kinase (dCK) is a rate-limiting enzyme in the deoxyribonucleoside salvage pathway and a critical determinant of therapeutic activity for several nucleoside analog pro-drugs. We have previously reported the development of (18)F-FAC, (1-(2′-deoxy-2′-(18)F-fluoro-β-D-arabinofuranosyl) cyt...

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Autori principali: Shu, Chengyi J., Campbell, Dean O., Lee, Jason T., Tran, Andrew Q., Wengrod, Jordan C., Witte, Owen N., Phelps, Michael E., Satyamurthy, Nagichettiar, Czernin, Johannes, Radu, Caius G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119947/
https://ncbi.nlm.nih.gov/pubmed/20554721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.109.073361
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