Long-chain acyl-CoA synthetase 4 modulates prostaglandin E(2) release from human arterial smooth muscle cells

Long-chain acyl-CoA synthetases (ACSLs) catalyze the thioesterification of long-chain FAs into their acyl-CoA derivatives. Purified ACSL4 is an arachidonic acid (20:4)-preferring ACSL isoform, and ACSL4 is therefore a probable regulator of lipid mediator production in intact cells. Eicosanoids play...

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Main Authors: Golej, Deidre L., Askari, Bardia, Kramer, Farah, Barnhart, Shelley, Vivekanandan-Giri, Anuradha, Pennathur, Subramaniam, Bornfeldt, Karin E.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2011
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053208/
https://ncbi.nlm.nih.gov/pubmed/21242590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M013292
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