Acyl-CoA Synthetase 1 Is Induced by Gram-negative Bacteria and Lipopolysaccharide and Is Required for Phospholipid Turnover in Stimulated Macrophages

The enzyme acyl-CoA synthetase 1 (ACSL1) is induced by peroxisome proliferator-activated receptor α (PPARα) and PPARγ in insulin target tissues, such as skeletal muscle and adipose tissue, and plays an important role in β-oxidation in these tissues. In macrophages, however, ACSL1 mediates inflammato...

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Bibliographic Details
Main Authors: Rubinow, Katya B., Wall, Valerie Z., Nelson, Joel, Mar, Daniel, Bomsztyk, Karol, Askari, Bardia, Lai, Marvin A., Smith, Kelly D., Han, Myoung Sook, Vivekanandan-Giri, Anuradha, Pennathur, Subramaniam, Albert, Carolyn J., Ford, David A., Davis, Roger J., Bornfeldt, Karin E.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Lipids
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617295/
https://ncbi.nlm.nih.gov/pubmed/23426369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.458372
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