Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1

The mechanisms that promote an inflammatory environment and accelerated atherosclerosis in diabetes are poorly understood. We show that macrophages isolated from two different mouse models of type 1 diabetes exhibit an inflammatory phenotype. This inflammatory phenotype associates with increased exp...

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Detalhes bibliográficos
Main Authors: Kanter, Jenny E., Kramer, Farah, Barnhart, Shelley, Averill, Michelle M., Vivekanandan-Giri, Anuradha, Vickery, Thad, Li, Lei O., Becker, Lev, Yuan, Wei, Chait, Alan, Braun, Kathleen R., Potter-Perigo, Susan, Sanda, Srinath, Wight, Thomas N., Pennathur, Subramaniam, Serhan, Charles N., Heinecke, Jay W., Coleman, Rosalind A., Bornfeldt, Karin E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311324/
https://ncbi.nlm.nih.gov/pubmed/22308341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111600109
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