Inflammatory stimuli induce acyl-CoA thioesterase 7 and remodeling of phospholipids containing unsaturated long (≥C20)-acyl chains in macrophages

Acyl-CoA thioesterase 7 (ACOT7) is an intracellular enzyme that converts acyl-CoAs to FFAs. ACOT7 is induced by lipopolysaccharide (LPS); thus, we investigated downstream effects of LPS-induced induction of ACOT7 and its role in inflammatory settings in myeloid cells. Enzymatic thioesterase activity...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Wall, Valerie Z., Barnhart, Shelley, Kramer, Farah, Kanter, Jenny E., Vivekanandan-Giri, Anuradha, Pennathur, Subramaniam, Bolego, Chiara, Ellis, Jessica M., Gijón, Miguel A., Wolfgang, Michael J., Bornfeldt, Karin E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454516/
https://ncbi.nlm.nih.gov/pubmed/28416579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M076489
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