Endothelial Acyl-CoA Synthetase 1 is not Required for Inflammatory and Apoptotic Effects of a Saturated Fatty Acid-Rich Environment

OBJECTIVE: Saturated fatty acids, such as palmitic and stearic acid, cause detrimental effects in endothelial cells (ECs) and have been suggested to contribute to macrophage accumulation in adipose tissue and the vascular wall in states of obesity and insulin resistance. Long-chain fatty acids are b...

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Hlavní autoři: Li, Xin, Gonzalez, Oscar, Shen, Xia, Barnhart, Shelley, Kramer, Farah, Kanter, Jenny E., Vivekanandan-Giri, Anuradha, Tsuchiya, Kyoichiro, Handa, Priya, Pennathur, Subramaniam, Kim, Francis, Coleman, Rosalind A., Schaffer, Jean E., Bornfeldt, Karin E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553857/
https://ncbi.nlm.nih.gov/pubmed/23241406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.252239
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