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Protein Kinase B Controls Transcriptional Programs that Direct Cytotoxic T Cell Fate but Is Dispensable for T Cell Metabolism

In cytotoxic T cells (CTL), Akt, also known as protein kinase B, is activated by the T cell antigen receptor (TCR) and the cytokine interleukin 2 (IL-2). Akt can control cell metabolism in many cell types but whether this role is important for CTL function has not been determined. Here we have shown...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Macintyre, Andrew N., Finlay, David, Preston, Gavin, Sinclair, Linda V., Waugh, Caryll M., Tamas, Peter, Feijoo, Carmen, Okkenhaug, Klaus, Cantrell, Doreen A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052433/
https://ncbi.nlm.nih.gov/pubmed/21295499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.01.012
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