Kindlin-3–mediated signaling from multiple integrin classes is required for osteoclast-mediated bone resorption

The blood cell–specific kindlin-3 protein is required to activate leukocyte and platelet integrins. In line with this function, mutations in the KINDLIN-3 gene in man cause immunodeficiency and severe bleeding. Some patients also suffer from osteopetrosis, but the underlying mechanism leading to abn...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Schmidt, Sarah, Nakchbandi, Inaam, Ruppert, Raphael, Kawelke, Nina, Hess, Michael W., Pfaller, Kristian, Jurdic, Pierre, Fässler, Reinhard, Moser, Markus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2011
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051823/
https://ncbi.nlm.nih.gov/pubmed/21357746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201007141
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller