Functional characterization of mutations in inherited human cPLA(2) deficiency

Group IVA cytosolic phospholipase A(2) (cPLA(2)α) catalyzes the first step in the arachidonic acid cascade leading to the synthesis of important lipid mediators, the prostaglandins and leukotrienes. We previously described a patient deficient in cPLA(2)α activity, which was associated with mutations...

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Main Authors: Reed, Kathleen, Tucker, Dawn E., Aloulou, Ahmed, Adler, David, Ghomashchi, Farideh, Gelb, Michael H., Leslie, Christina C., Oates, John A., Boutaud, Olivier
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051024/
https://ncbi.nlm.nih.gov/pubmed/21247147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101877n
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