Functional characterization of mutations in inherited human cPLA(2) deficiency

Group IVA cytosolic phospholipase A(2) (cPLA(2)α) catalyzes the first step in the arachidonic acid cascade leading to the synthesis of important lipid mediators, the prostaglandins and leukotrienes. We previously described a patient deficient in cPLA(2)α activity, which was associated with mutations...

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Hauptverfasser: Reed, Kathleen, Tucker, Dawn E., Aloulou, Ahmed, Adler, David, Ghomashchi, Farideh, Gelb, Michael H., Leslie, Christina C., Oates, John A., Boutaud, Olivier
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051024/
https://ncbi.nlm.nih.gov/pubmed/21247147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101877n
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