Inherited human cPLA(2α) deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction

Cytosolic phospholipase A(2α )(cPLA(2α)) hydrolyzes arachidonic acid from cellular membrane phospholipids, thereby providing enzymatic substrates for the synthesis of eicosanoids, such as prostaglandins and leukotrienes. Considerable understanding of cPLA(2α )function has been derived from investiga...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Adler, David H., Cogan, Joy D., Phillips, John A., Schnetz-Boutaud, Nathalie, Milne, Ginger L., Iverson, Tina, Stein, Jeffrey A., Brenner, David A., Morrow, Jason D., Boutaud, Olivier, Oates, John A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2350426/
https://ncbi.nlm.nih.gov/pubmed/18451993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30473
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker