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Quantification of Protein Phosphorylation by Liquid Chromatography−Mass Spectrometry

The identification and quantification of specific phosphorylation sites within a protein by mass spectrometry has proved challenging when measured from peptides after protein digestion because each peptide has a unique ionization efficiency that alters with modification, such as phosphorylation, and...

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Autors principals: Previs, Michael J., VanBuren, Peter, Begin, Kelly J., Vigoreaux, Jim O., LeWinter, Martin M., Matthews, Dwight E.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2008
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050605/
https://ncbi.nlm.nih.gov/pubmed/18605695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac800337v
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