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Quantification of 2-Hydroxyglutarate Enantiomers by Liquid Chromatography-mass Spectrometry

Two enantiomers of 2-hydroxyglutarate (2HG), L (L2HG) and D (D2HG), are metabolites of unknown function in mammalian cells that were initially associated with separate and rare inborn errors of metabolism resulting in increased urinary excretion of 2HG linked to neurological deficits in children (Ch...

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Détails bibliographiques
Publié dans:Bio Protoc
Auteurs principaux: Oldham, William M., Loscalzo, Joseph
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448426/
https://ncbi.nlm.nih.gov/pubmed/28573160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.1908
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