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Targets of somatic hypermutation within immunoglobulin light chain genes in zebrafish
In mammals, somatic hypermutation (SHM) of immunoglobulin (Ig) genes is critical for the generation of high-affinity antibodies and effective immune responses. Knowledge of sequence-specific biases in the targeting of somatic mutations can be useful for studies aimed at understanding antibody repert...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Science Inc
2011
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3050447/ https://ncbi.nlm.nih.gov/pubmed/21070232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03358.x |
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