Nitric Oxide Mediates Relative Airway Hyporesponsiveness to Lipopolysaccharide in Surfactant Protein A–Deficient Mice

Surfactant protein A (SP-A) mediates innate immune cell responses to LPS, a cell wall component of gram-negative bacteria that is found ubiquitously in the environment and is associated with adverse health effects. Inhaled LPS induces lung inflammation and increases airway responsiveness (AR). Howev...

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Main Authors: Pastva, Amy M., Walker, Julia K. L., Maddox, Lee A., Mukherjee, Sambuddho, Giamberardino, Charles, Hsia, Bethany, Potts, Erin, Zhu, Hongmei, Degan, Simone, Sunday, Mary E., Lawson, Barbara L., Korfhagen, Thomas R., Schwartz, David A., Eu, Jerry P., Foster, William M., McMahon, Timothy J., Que, Loretta, Wright, Jo Rae
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2011
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049231/
https://ncbi.nlm.nih.gov/pubmed/20348208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0284OC
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