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Increased Nitric Oxide Production Prevents Airway Hyperresponsiveness in Caveolin-1 Deficient Mice Following Endotoxin Exposure

BACKGROUND: Caveolin-1, the hallmark protein of caveolae, is highly expressed within the lung in the epithelium, endothelium, and in immune cells. In addition to its classical roles in cholesterol metabolism and endocytosis, caveolin-1 has also been shown to be important in inflammatory signaling pa...

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Detalhes bibliográficos
Main Authors: Hsia, Bethany J., Pastva, Amy M., Giamberardino, Charles D., Potts-Kant, Erin N., Foster, W. Michael, Que, Loretta G., Abraham, Soman N., Wright, Jo Rae, Zaas, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836011/
https://ncbi.nlm.nih.gov/pubmed/24273688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-6121.S1-004
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