Increased Nitric Oxide Production Prevents Airway Hyperresponsiveness in Caveolin-1 Deficient Mice Following Endotoxin Exposure

BACKGROUND: Caveolin-1, the hallmark protein of caveolae, is highly expressed within the lung in the epithelium, endothelium, and in immune cells. In addition to its classical roles in cholesterol metabolism and endocytosis, caveolin-1 has also been shown to be important in inflammatory signaling pa...

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Main Authors: Hsia, Bethany J., Pastva, Amy M., Giamberardino, Charles D., Potts-Kant, Erin N., Foster, W. Michael, Que, Loretta G., Abraham, Soman N., Wright, Jo Rae, Zaas, David W.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836011/
https://ncbi.nlm.nih.gov/pubmed/24273688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-6121.S1-004
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