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Surfactant Protein-A modulates induction of regulatory T cells via Transforming Growth Factor β

T cell receptor (TCR) signaling plays a critical role in regulatory T cell (Treg) development. However, the mechanism for tissue specific induction of Tregs in the periphery remains unclear. We observed that surfactant protein A (SP-A) deficient mice have impaired expression of Foxp3 and fewer CD25+...

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Autors principals: Mukherjee, Sambuddho, Giamberardino, Charles, Thomas, Joseph M., Gowdy, Kymberly, Pastva, Amy M., Wright, Jo Rae
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331948/
https://ncbi.nlm.nih.gov/pubmed/22474025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101775
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