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Nitric Oxide Mediates Relative Airway Hyporesponsiveness to Lipopolysaccharide in Surfactant Protein A–Deficient Mice

Surfactant protein A (SP-A) mediates innate immune cell responses to LPS, a cell wall component of gram-negative bacteria that is found ubiquitously in the environment and is associated with adverse health effects. Inhaled LPS induces lung inflammation and increases airway responsiveness (AR). Howev...

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Bibliografiske detaljer
Main Authors: Pastva, Amy M., Walker, Julia K. L., Maddox, Lee A., Mukherjee, Sambuddho, Giamberardino, Charles, Hsia, Bethany, Potts, Erin, Zhu, Hongmei, Degan, Simone, Sunday, Mary E., Lawson, Barbara L., Korfhagen, Thomas R., Schwartz, David A., Eu, Jerry P., Foster, William M., McMahon, Timothy J., Que, Loretta, Wright, Jo Rae
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049231/
https://ncbi.nlm.nih.gov/pubmed/20348208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0284OC
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