Nitric Oxide Mediates Relative Airway Hyporesponsiveness to Lipopolysaccharide in Surfactant Protein A–Deficient Mice

Surfactant protein A (SP-A) mediates innate immune cell responses to LPS, a cell wall component of gram-negative bacteria that is found ubiquitously in the environment and is associated with adverse health effects. Inhaled LPS induces lung inflammation and increases airway responsiveness (AR). Howev...

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Autori principali: Pastva, Amy M., Walker, Julia K. L., Maddox, Lee A., Mukherjee, Sambuddho, Giamberardino, Charles, Hsia, Bethany, Potts, Erin, Zhu, Hongmei, Degan, Simone, Sunday, Mary E., Lawson, Barbara L., Korfhagen, Thomas R., Schwartz, David A., Eu, Jerry P., Foster, William M., McMahon, Timothy J., Que, Loretta, Wright, Jo Rae
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049231/
https://ncbi.nlm.nih.gov/pubmed/20348208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0284OC
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