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Development of Tumor-infiltrating CD8+ T cell Memory Precursor Effector Cells (MPECs) and Anti-melanoma Memory Responses are the Result of Vaccination and TGF-β Blockade During the Perioperative Period of Tumor Resection

A main goal of cancer immunology research is the formation of antigen-specific memory T cell immunity capable of activation upon tumor re-encounter. The requirements necessary to overcome the inhibitory signals present in the tumor microenvironment and form such memory T cell responses are unknown....

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Autors principals: Bellavance, Emily C., Kohlhapp, Frederick J., Zloza, Andrew, O’Sullivan, Jeremy A., McCracken, James, Jagoda, Michael C., Lacek, Andrew T., Posner, Mitchell C., Guevara-Patino, Jose A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048906/
https://ncbi.nlm.nih.gov/pubmed/21289306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002549
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