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Regulation of Ribosomal Protein S6 Phosphorylation by Casein Kinase 1 and Protein Phosphatase 1

Ribosomal protein S6 (rpS6) is a critical component of the 40 S ribosomal subunit that mediates translation initiation at the 5′-m(7)GpppG cap of mRNA. In response to mitogenic stimuli, rpS6 undergoes ordered C-terminal phosphorylation by p70 S6 kinases and p90 ribosomal S6 kinases on four conserved...

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Detalhes bibliográficos
Main Authors: Hutchinson, John A., Shanware, Naval P., Chang, Haeyoon, Tibbetts, Randal S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048750/
https://ncbi.nlm.nih.gov/pubmed/21233202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.141754
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