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Recovery of Small Infectious PrP(res) Aggregates from Prion-infected Cultured Cells
Prion diseases are characterized by deposits of abnormal conformers of the PrP protein. Although large aggregates of proteinase K-resistant PrP (PrP(res)) are infectious, the precise relationships between aggregation state and infectivity remain to be established. In this study, we have fractionated...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048700/ https://ncbi.nlm.nih.gov/pubmed/21212268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165233 |
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