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Conserved core of amyloid fibrils of wild type and A30P mutant α-synuclein
The major component of neural inclusions that are the pathological hallmark of Parkinson's disease are amyloid fibrils of the protein α-synuclein (aS). Here we investigated if the disease-related mutation A30P not only modulates the kinetics of aS aggregation, but also alters the structure of a...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048423/ https://ncbi.nlm.nih.gov/pubmed/21280130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.570 |
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