DAI (DLM-1/ZBP1) as a Genetic Adjuvant for DNA Vaccines That Promotes Effective Antitumor CTL Immunity

DNA vaccination is an attractive approach to induce antigen-specific cytotoxic CD8(+) T lymphocytes (CTLs), which can mediate protective antitumor immunity. The potency of DNA vaccines encoding weakly immunogenic tumor-associated antigens (TAAs) can be enhanced by codelivering gene-encoded adjuvants...

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Detalhes bibliográficos
Main Authors: Lladser, Alvaro, Mougiakakos, Dimitrios, Tufvesson, Helena, Ligtenberg, Maarten A, Quest, Andrew FG, Kiessling, Rolf, Ljungberg, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048184/
https://ncbi.nlm.nih.gov/pubmed/21157438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.268
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