NF-κB activation during intradermal DNA vaccination is essential for eliciting tumor protective antigen-specific CTL responses

DNA vaccines have been shown to elicit tumor-protective cytotoxic T lymphocyte (CTL) immunity in preclinical models, but have shown limited efficacy in cancer patients. Plasmids used for DNA vaccines can stimulate several innate immune receptors, triggering the activation of master transcription fac...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Ligtenberg, Maarten A, Rojas-Colonelli, Nicole, Kiessling, Rolf, Lladser, Alvaro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906403/
https://ncbi.nlm.nih.gov/pubmed/23884215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.25699
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi