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NF-κB activation during intradermal DNA vaccination is essential for eliciting tumor protective antigen-specific CTL responses
DNA vaccines have been shown to elicit tumor-protective cytotoxic T lymphocyte (CTL) immunity in preclinical models, but have shown limited efficacy in cancer patients. Plasmids used for DNA vaccines can stimulate several innate immune receptors, triggering the activation of master transcription fac...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3906403/ https://ncbi.nlm.nih.gov/pubmed/23884215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.25699 |
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