Adeno-associated Virus Vectors Serotype 2 Induce Prolonged Proliferation of Capsid-Specific CD8(+) T Cells in Mice

Using adoptive transfer models we determined that an adeno-associated viral vector of serotype 2 (AAV2) induces in mice proliferation of CD8(+) T cells that recognize an epitope within the viral capsid. Proliferation to an endogenous epitope within viral protein (VP)3 could be observed for at least...

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Bibliografiska uppgifter
Huvudupphovsmän: Li, Hua, Tuyishime, Steven, Wu, Te-Lang, Giles-Davis, Wynetta, Zhou, Dongming, Xiao, Weidong, High, Katherine A, Ertl, Hildegund CJ
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2011
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Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048183/
https://ncbi.nlm.nih.gov/pubmed/21157435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.267
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