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Hexon-modified Recombinant E1-deleted Adenovirus Vectors as Dual Specificity Vaccine Carriers for Influenza Virus

To determine if an ordered and repetitive display of an epitope promoted induction of superior antibody responses, we compared B-cell responses to an influenza A virus epitope that was either encoded as a transgene by an adenovirus (Ad) vector or expressed on the vector's surface. To this end,...

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Detalhes bibliográficos
Main Authors: Zhou, Dongming, Wu, Te-Lang, Emmer, Kristel L, Kurupati, Raj, Tuyishime, Steven, Li, Yan, Giles-Davis, Wynetta, Zhou, Xiangyang, Xiang, Zhiquan, Liu, Qin, Ratcliffe, Sarah J, Ertl, Hildegund CJ
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589160/
https://ncbi.nlm.nih.gov/pubmed/23229092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.248
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