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Disparate chromatin landscapes and kinetics of inactivation impact differential regulation of p53 target genes

The p53 transcription factor regulates the expression of genes involved in cellular responses to stress, including cell cycle arrest and apoptosis. The p53 transcriptional program is extremely malleable, with target gene expression varying in a stress- and cell type-specific fashion. The molecular m...

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Detalhes bibliográficos
Main Authors: Gomes, Nathan P, Espinosa, Joaquín M
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047614/
https://ncbi.nlm.nih.gov/pubmed/20818159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.17.12998
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